Roy Taylor, professor of medicine and metabolism at Translational and Clinical Research Institute at Newcastle University upon Tyne in the U.K. The biggest factor in whether a person can lower blood sugar below diabetic levels and keep it there without medication is the amount of time that has passed since diagnosis, according to Dr. Sustained remission was linked to keeping the weight off. or more were most likely to achieve remission.įollow-up research, published in The Lancet Diabetes & Endocrinology in 2019, found that one-third of participants remained in remission at the two-year mark. The research was carried out in primary-care practices-not specialized weight-loss centers-over a period of a year.
#Lost to time goodreada trial#
The DiRECT trial published in the Lancet in 2018 found that nearly half (46%) of 149 participants studied-who had been diagnosed with Type 2 diabetes within six years and who weren’t on insulin-were able to achieve remission through an evidence-based weight-loss program. A closer look reveals that weight loss can cut fat levels inside the liver and pancreas, letting those organs function normally and allowing them to better regulate blood–glucose levels.Īnd remission isn’t accessible just to a select few.
Some research suggests that after gastric-bypass surgery is performed, certain gut hormones stimulate the production of insulin in the body, including what’s called glucagon-like peptide-1 (GLP-1) and peptide tyrosine-tyrosine (PYY), which drive down blood-sugar levels.īut although remission is strongly associated with bariatric surgery, prominent research shows that significant weight loss alone-without surgery-can be enough to put Type 2 diabetes into remission. In addition to the pounds dropped, he adds that there may be secretion of hormones as a result of the surgical reconfiguration of the gastrointestinal tract that makes remission more likely. “The most common place we see is with bariatric surgery where there’s significant weight loss,” Gabbay says. Read More: How People With Type 2 Diabetes Can Lower Their Risk of Health Problems Something to strive for, or a rare phenomenon?Īdvances in the treatment of Type 2 diabetes may put remission within reach for more people with the disease, especially those who have been more recently diagnosed. And experts stress that continued follow-up with health care providers-not only to monitor blood glucose but also to check for diabetes complications-is important because the impact of diabetes remission (fleeting or long-lasting) on things like heart health and death rate isn’t yet well understood. That would be below, for example, 6.5% A1c, for the blood test that’s used to get a three-month average of blood sugar.īut a lot still remains unclear-like how long remission generally lasts, because it varies. In simplest terms, the expert panel defined Type 2 diabetes remission as having a blood-sugar level below the established threshold for a diabetes diagnosis for at least three months without taking diabetes medication. Robert Gabbay, ADA’s chief science and medical officer. “The reason we use the word remission is because if someone were to think that they were cured or reversed, the challenge is they may then not feel like they need to have anything checked,” says Dr.
The concept of Type 2 diabetes remission, which is getting increasing attention from researchers and doctors, also goes by other names, including diabetes “reversal,” “resolution,” and even “cure.” But a consensus of experts led by the ADA last year agreed on the term remission as being most accurate. “I share my story with anybody who will listen, in hopes that it can make a difference.” Diabetes ‘reversal’ by another name
“I’m the type of person who wants to be in control of my health,” says Wilson, who continues to be vigilant about monitoring his blood sugar.
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